The Dosenbach Lab is seeking a postdoctoral research associate to work on precision functional mapping (PFM) data in clinical and control populations, as well as a large (n=11,874) developmental cohort (ABCD). We are focused on pushing functional MRI (fMRI) and resting state functional connectivity MRI (RSFC) acquisition and analysis methodology to the level of individual patients. In order to create and annotate the functional connectomes of individual patients, we must improve the signal-to-noise, spatial resolution and replicability of fMRI and RSFC data. Precise, high fidelity individual connectomes are a requirement for RSFC based diagnostics and RSFC guided individualized psychological and psychiatric treatments. Therefore, we have developed a novel approach for studying individual patients with functional neuroimaging: Individual-specific Precision Functional Mapping. In order to further improve neuropsychiatric treatments, we must find ways to relate underlying brain network changes to changes in behavior. To that end, we have been conducting longitudinal, multimodal MRI research in children with hemiplegia undergoing Constraint-Induced Movement Therapy (CIMT), children with perinatal stroke and children pre/post hemispherotomy for intractable epilepsy, as well as healthy volunteers. These studies have benefited from our recent methodological advances in motion monitoring, single-subject analyses and machine learning. Therefore, we are now in a position to apply our novel Precision Functional Mapping approach to study children across a number of diagnostic cohorts (ASD, ADHD, TS). The postdoctoral research associate will have the opportunity to work with all of our frequent collaborators, including but not limited to, Drs. Damien Fair, Deanna Barch, Chad Sylvester, Deanna Greene and Marc Raichle. They will be able to draw on Washington University’s world class systems neuroscience and neuroimaging facilities and develop independent projects. In addition to high-quality research facilities, career and professional development training for postdoctoral research associates is provided through the Office of Postdoctoral Affairs, Career Center, Teaching Center, and campus groups. Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs.
Supervisor: Nico Dosenbach MD, PhD
Closing date: 5/1/2020